Xuxia Wang1, Fuchun Lin2, Hao Lei1
1State Key Laboratory of
Magnetic Resonance & Atomic & Molecular Physics, Wuhan Institute of
Physics & Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, China,
People's Republic of; 2State Key Laboratory of Magnetic Resonance
& Atomic & Molecular Physics , Wuhan Institute of Physics &
Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, China, People's
Republic of
The white matter (WM) lesions evolution of rat brain induced by bilateral common carotic arteries occlusion (BCCAO) were well studied previously by different ex vivo experiments, yet not well studied in vivo by an noninvasive detection methods. And diffusion tensor imaging (DTI) was used increasing to noninvasively evaluate the WM damage and more sensitivity than conventional T1 and T2 weighted images. In this study, the optic tract (OT) of BCCAO rat brain damage evolution was investigated. The results showed that in OT reduced the fractional anisotropy (FA) and axial diffusivity (ADC), increased radial diffusivity (ADC) were occured during the detecting period compared to control.
Keywords