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Abstract #2334

HARDI Fiber Tracking is Necessary to Delineate the Auditory Radiation

Jeffrey I. Berman1,2, Timothy P. L. Roberts1,2

1Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, United States; 2Radiology, University of Pennsylvania, Philadelphia, PA, United States

It is necessary to develop robust methods of delineating the entire auditory radiation for quantitative studies in children with autism or language impairments. This work demonstrates the consistent ability of high angular resolution diffusion imaging (HARDI) fiber tracking to delineate the full length of the auditory radiation in a population of children. Diffusion MR was acquired from 6 children with autism spectrum disorder and 3 control children on a 3T Siemens scanner. The ability of HARDI and DTI fiber tracking to delineate the full auditory radiation were compared. HARDI fiber tracking successfully delineated the auditory radiation at a significantly higher rate than DTI fiber tracking.