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Abstract #2358

Rapid Acquisition of Targeted High Resolution Human Brain Images using a Combined SENSE, Inner Volume Imaging & Multi-Shot EPI Spin Echo Sequence at 7T

Christopher Joseph Wargo1,2, John Christopher Gore1,2

1Vanderbilt University Institute of Imaging Science, Nashville, TN, United States; 2Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States

In this abstract, we present the combination of SENSE, Zoom Inner Volume Imaging (IVI), and a multi-shot EPI spin echo sequence to rapidly achieve 160 to 350 μm resolutions for targeted imaging of a variety of in vivo human brain regions, with 46 to 429 fold accelerations achieved in multi-slice and 3D volume images, and scan times between three to six minutes. Areas targeted included the midbrain, cortex, thalamus, lentiform, hippocampus, and corpus callosum with visible gray and white matter contrast, small blood vessel identification, and substructure localization within each region.