Meeting Banner
Abstract #2448

Changes in the Brain More Than 10 Years After Liver Transplantation

Vt Herynek1, Monika Dezortov1, Dita Wagnerov1, Irena Hejlov2, Milan Hjek1

1MR-unit, Department of Diagnostic & Interventional Radiology, Institute for Clinical & Experimental Medicine, Prague, Czech Republic; 2Hepatogastroenterology Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic


Hepatic encephalopathy in patients with liver disease manifests itself by hyperintense (T1-weighted images) or hypointense (T2-weighted images) signals in the basal ganglia due to deposition of paramagnetic ions. This process is reversible by liver transplantation. These changes can be assessed by relaxometry. We collected a unique group of 37 patients transplanted 8-15 years ago, which was compared to a group of patients before liver transplantation and a group of patients measured within two years after. Relaxometry revealed that recovery in the basal ganglia is permanent and no recurrence of paramagnetic ions was observed even after 15 years.

Keywords