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Abstract #2460

Prospects for Quantitative Imaging of Myelin with Dual-Echo Short Inversion Time 3D UTE MRI

Michael J. Wilhelm1, Henry H. Ong1, Suzanne L. Wehrli2, Ping-Huei Tsai1, David B. Hackney3, Felix W. Wehrli1

1Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2NMR Core Facility, Children's Hospital of Philadelphia, Philadelphia, PA, United States; 3Department of Radiology & Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, United States

Current MRI methods indirectly assess myelin by detecting myelin-associated water. Directly imaging myelin would enhance understanding of