Mark Steven Brown1, Peter Teale2,
Dan Collins2, Bryce Pasko2, Debra Singel3,
Don C. Rojas2, Martin Reite2
1Radiology, University of
Colorado Denver, Aurora, CO, United States; 2Psychiatry, University
of Colorado Denver, Aurora, CO, United States; 3Brain Imaging
Center, University of Colorado Denver, Aurora, CO, United States
1H-MRS measurements of GABA/Cr correlate with MEG determined auditory evoked gamma band phase locking measurements in normal adult controls. The results suggest that MEG auditory evoked phase locking may be an index of GABAergic inhibitory interneuronal activity as indexed by GABA concentration. No previous studies have correlated MRS determined GABA concentration with auditory MEG phase locking metrics.
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