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Abstract #2615

k-Space Sampling Approaches using TWIST: Implications for Dynamic Contrast Acquisitions

Xin Li1, John W. Grinstead2, Cecily V. Bishop3, Ian J. Tagge1, Richard L. Stouffer3,4, William D. Rooney1, Gerhard Laub5

1Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, United States; 2Siemens Healthcare, Portland, OR, United States; 3Division of Reproductive Sciences, ONPRC, Oregon Health & Science University, Portland, OR, United States; 4Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR, United States; 5Siemens Healthcare, San Francisco, CA, United States


Time-resolved angiography with stochastic trajectories (TWIST) pulse sequence offers a practical and flexible way to perform sub-second, time-sequential 3D measurements. It is often used in combination with contrast injection to provide dynamic clinical information. Using a primate model (rhesus macaque) and simulated data therein, we investigated TWIST center of k-space updating strategy on Dynamic-Contrast-Enhanced (DCE) MRI signal time-course and image.