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Abstract #2648

Rapid Quantitative T2 Imaging of Prostate Cancer using a Reduced FOV Single-Shot Fast-Spin-Echo Sequence

Lawrence Patrick Panych1, Renxin Chu1, Yi Tang1, Stephan E. Maier1, Clare M. Tempany1, Robert V. Mulkern2

1Radiology, Brigham & Womens Hospital, Boston, MA, United States; 2Radiology, Children's Hospital, Boston, MA, United States

A reduced field-of-view single-shot fast-spin-echo sequence was implemented and applied for T2 quantification in the prostate. Six patients with biopsy-proven prostate cancer were imaged, acquiring whole-gland multiple-TE images in around one minute. Apparent T2 values were estimated from the multi-TE data for regions selected as being suspected healthy (SH) and suspected cancerous (SC). The apparent T2 in the SH regions was estimated at 224 67 msec and 129 25 msec in the SC regions. Sensitivity and specificity for detection of cancerous tissue is estimated to be 82% and 80% with this sequence.