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Abstract #2658

Whole-Brain Voxel-Based Susceptibility-Weighted Imaging (SWI) Analysis: Normal Cortical & Subcortical Values, & Preliminary Results in Post-Traumatic Epilepsy

Hugo Alexandre Ferreira1, Alexandre Andrade1, Rui M. Manaas2,3, Pedro Miguel Gonalves-Pereira3,4

1Instituto de Biofsica e Engenharia Biomdica, Faculdade de Cincias da Universidade de Lisboa, Lisboa, Portugal; 2Servio de Neurorradiologia, Hospital dos Capuchos, Lisboa, Portugal; 3Servio de Radiologia, Hospital dos Lusadas, Lisboa, Portugal; 4Escola Superior de Tecnologias da Sade, Instituto Politcnico de Lisboa, Lisboa, Portugal

An automated voxel-based analysis method of Susceptibility-Weighted Imaging (SWI) data was developed in combination with automated masks of brain structures to determine normal tissue values. Significant changes were observed with age and gender. A preliminary study comparing normal subjects to post-traumatic epilepsy (PTE) patients demonstrated changes in tissue magnetic susceptibility within limbic and mesencephalic structures.