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Abstract #2734

Reference Free Localization & Quantification of Contrast Agents using Relaxivity Dispersion at 1.5T

Uvo Christoph Hoelscher1, Steffen Lother1, Florian Fidler1, Peter Jakob1,2

1Research Center Magnetic Resonance Bavaria (MRB), Wuerzburg, Bavaria, Germany; 2Department for Experimental Physics 5 (Biophysics), University of Wuerzburg, Wuerzburg, Germany

Many medical problems can benefit from unambiguous localization and quantification of contrast agents, but conventional detection / quantification methods always require reference scans to separate contrast agent and tissue. In this work we present a new method to acquire both information without the need for a reference scan. The technique exploits relaxivity dispersion of the contrast agent making separation between contrast agent and tissue unambiguous. Resulting images show pure contrast agent signal and can be used to determine concentrations.