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Abstract #2746

Accelerated T1 & T2 Relaxometry in the Human Brain using UNFOLD

Ana-Maria Oros-Peusquens1, Nadim Jon Shah1,2

1Institute of Neuroscience & Medicine (INM-4), Research Centre Juelich, Juelich, NA, Germany; 22Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, Germany


We present an application of the UNFOLD method to T1 and T2 relaxometry which takes advantage of the high temporal resolution of two multi-point mapping methods; the inherent and extensive temporal information is used for acquisition time reduction. A multi-time-point, multi-slice Look-Locker sequences, TAPIR, was used for T1 mapping and a conventional CPMG-type multi-slice multi-echo sequence for T2 mapping. Comparing full k-t space and undersampled k-t space, the mean value over the brain is below 3%; the undersampled acquisition is, however, twice as fast.