Abstract #2755

A New 3D Method for Water and Relaxation Time Mapping: Comparison to the 2D gold Standard

Ana Maria Oros-Peusquens¹, Fabian Keil¹, Vincent Gras¹, Zaheer Abbas¹, Daniel Brenner¹, Miriam Rabea Kubach¹, Klaus Hans Mannfred Mllenhoff¹, Nadim Jon Shah^1,2

¹Institute of Neuroscience & Medicine - 4, Forschungszentrum Juelich, Juelich, Germany; ²Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, Germany

A new 3D method for water content and relaxation time mapping in which the M0 and T1 are determined from a two-point fit to measured data sets is presented. The method is based on 3D multiple-echo gradient echo acquisitions and thus also allows for accurate determination of T2*. The new method is applied at 3T and compared to a gold standard 2D method with very long TR. Results from phantoms and 5 healthy subjects are presented. The accuracy of the 3D method is better than 5%.