Strategies for Fast 3D Volumetric Coverage using Spatiotemporally-Encoded MRI

Noam Ben-Eliezer¹, Lucio Frydman¹

The generation of 2D NMR images in a single-scan is a common ingredient in a variety of applications. Real life applications, however, often require 3D volumetric coverage, while keeping the overall scanning on a sub-second timescale. Current ultrafast 3D methods are based on EPI, which notwithstanding its proven success is still challenged by B0 heterogeneities and/or multiple chemical sites. We explore here a new approach, based on combining spatiotemporal-encoding with super-resolution reconstruction algorithms, to achieve higher immunity to these artifacts. A number of 3D sequence schemes are presented and demonstrated on in-vivo mouse models.