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Abstract #2923

Slice-By-Slice Grey Matter Optimised Z-Shimming for fMRI Applications

Stephen James Wastling1, David John Lythgoe1, Gareth John Barker1

1Centre for Neuroimaging Sciences, Institute of Psychiatry, King's College London, London, United Kingdom

Previous workers have shown the feasibility of recovering signal in regions of GE-EPI images with susceptibility-induced signal dropout by combining two images acquired using different z-shim gradients. We have demonstrated that by constraining the algorithm used to select the two z-shims to grey matter voxels on a slice-by-slice basis improves signal recovery over their whole-brain optimisation scheme.