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Abstract #2939

Fluid Suppression for MRI Screening by Dual Echo Subtraction

Ananth J. Madhuranthakam1, Karen S. Lee2, Jean H. Brittain3, Ivan Pedrosa2, Neil M. Rofsky4, David C. Alsop2

1Global Applied Science Laboratory, GE Healthcare, Boston, MA, United States; 2Radiology, Beth Israel Deaconess Medical Center & Harvard Medical School, Boston, MA, United States; 3Global Applied Science Laboratory, GE Healthcare, Madison, WI, United States; 4Radiology, UT Southwestern Medical Center, Dallas, TX, United States

T2 techniques such as STIR provide excellent contrast for tumor screening but bright signal from fluid complicates interpretation. We propose dual echo single-shot RARE based approach to filter out very long T2 fluid while preserving T2 sensitivity for lesions. Following spectrally selective inversion for fat suppression, a long echo train is used to acquire two single-shot images. Subtraction of the longer TE image from the shorter one effectively suppresses fluid. This motion insensitive approach is faster, has higher sensitivity, and less T1 dependent than FLAIR suppression approaches. The feasibility of the technique is demonstrated in normal volunteers and tumor models.