Abstract #2943

Measurement of Field Inhomogeneity & Susceptibility Effects for Liver Iron Quantification in Patients with Iron Overload

Brian A. Taylor¹, Ralf B. Loeffler¹, Ruitian Song¹, R. Jason Stafford², Beth McCarville¹, Jane S. Hankins³, Claudia M. Hillenbrand¹

¹Radiological Sciences, St. Jude Children's Research Hospital, Memphis, TN, United States; ²Imaging Physics, the University of Texas M. D. Anderson Cancer Center, Houston, TX, United States; ³Hematology, St. Jude Children's Research Hospital, Memphis, TN, United States

An autoregressive moving average (ARMA) model was used to calculate field inhomogeneities in T2* imaging of the liver in patients with iron overload. Comparisons were made between ARMA T2* measurements and T2* from monoexponential fits calibrated to liver iron content measurements via biopsy.