Umer Abdur Rahim Khan1, Pierre Hugues Vivier1, Pippa Storey1, Akira Yamamoto1, Henry Rusinek1, Lei Zhang1, Kristopher Tantillo1, Ruth Lim1, James Babb1, John Devon2, David Stoffel1, Lewis Teperman2, Judith Benstein3, Samuel Sigal3, Edward Skolnik3, Vivian S. Lee1
1Radiology, New York University Langone Medical Center, New York, NY, United States; 2Surgery, New York University Langone Medical Center, New York, NY, United States; 3Internal Medicine, New York University Langone Medical Center, New York, NY, United States
Liver cirrhosis patients are frequently affected by renal compromise with the progression of the disease. In this patient population, and as reported for other pathologies previously, visual decrease in cortico-medullary differentiation (CMD) is observed with increasing renal insufficiency by T1-weighted MRI. We explored differences in T1 values for renal medulla and cortex and their role in producing decreased visual differentiation within the failing kidney. Our results suggest decreasing medullary T1 values to be responsible for loss of CMD with the progression of renal failure in cirrhotic patients.