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Abstract #3019

Optimising Oral Contrast Agents for Interactive Neonatal Gut Imaging

Owen John Arthurs1, Martin John Graves1, Ilse Joubert1, David John Lomas1

1Radiology, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom

The optimal contrast medium for neonatal gut MR imaging is unclear. Here, we investigate the relative T1 properties of several different potential agents to provide optimal signal. We then tested a variable IR pulse during interactive SSFSE imaging to existing bowel fluid and demonstrate feasibility. An optimal in-vitro TI of 500 - 800ms gave maximal signal difference between pineapple juices and milk, but in-vivo this was 1000 ms. Application of an optimally timed IR pulse can allow for improved contrast medium imaging in this sensitive population.