Kang Wang1, Frank Korosec1,2, Mark Schiebler2, Christopher Francois2, Scott Reeder2,3, Thomas Grist2, Reed Busse4, James Holmes4, Jean Brittain4, Nathan Artz1, Sean Fain1,3, Scott Nagle2
1Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 2Radiology, University of Wisconsin-Madison, Madison, WI, United States; 3Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States; 4Applied Science Lab, GE Healthcare, Madison, WI, United States
MR pulmonary perfusion is well suited for studying the pulmonary circulation and understanding the physiology and pathology of the lung. However, MR pulmonary perfusion has been challenging due to the requirements for large spatial coverage, high temporal resolution, and high spatial resolution. The purpose of this study is to demonstrate the feasibility of obtaining high isotropic spatial resolution 3D dynamic pulmonary perfusion images of the whole chest with very high temporal resolution. The technique combines a previously developed Interleaved Variable Density sampling method with parallel imaging and Cartesian HYPR reconstruction.