Abstract #3103

Clinical Application of Pharmacokinetic Analysis as a Biomarker in Solitary Pulmonary Nodules: Dynamic Contrast Enhanced MR Imaging

Hatsuho Mamata^1,2, Junichi Tokuda^1,2, Ritu R. Gill^1,2, Robert F. Padera^2,3, Robert E. Lenkinski^2,4, David J. Sugarbaker^2,5, Hiroto Hatabu^1,2

¹Radiology, Brigham & Women's Hospital, Boston, MA, United States; ²Harvard Medical School, Boston, MA, United States; ³Pathology, Brigham & Women's Hospital, Boston, MA, United States; ⁴Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; ⁵Thoracic surgery, Brigham & Women's Hospital, Boston, MA, United States

DCE-MRI indices and parameters were evaluated, especially focused on clinical application of pharmacokinetic analysis in solitary pulmonary nodules. kep value may be a potential biomarker to distinguish between malignant and benign tumors.