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Abstract #3123

Preliminary Result of Pharmacokinetic Parameter Evaluation in Malignant Pleural Mesothelioma: Correlation with Histology & Growth Type.

Hatsuho Mamata1,2, Ritu R. Gill1,2, Junichi Tokuda1,2, Robert F. Padera2,3, Robert E. Lenkinski2,4, William G. Richards2,5, Tamara R. Tilleman2,5, David J. Sugarbaker2,5, Hiroto Hatabu1,2

1Radiology, Brigham & Women's Hospital, Boston, MA, United States; 2Harvard Medical School, Boston, MA, United States; 3Pathology, Brigham & Women's Hospital, Boston, MA, United States; 4Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 5Thoracic surgery, Brigham & Women's Hospital, Boston, MA, United States


Pharmacokinetic parameters correlate with growth type and age of malignant pleural mesothelioma (MPM), however, they do not have correlation with histological subtype. Ktrans, kep and time-intensity curve type may reflect inflammatory component of diffuse pleural thickening type MPM.

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