Yonggang Lu1, Jacobus F. A. Jansen2, Hilda E. Stambuk1, Yousef Tehrani-Mazaheri1, Nancy Lee1, Jason A. Koutcher1, Amita Shukla-Dave1
In the present study, correlation of quantitative parameters derived from IVIM- and DCE- MRI techniques was performed in neck nodal metastases. The results showed that D* (pseudo-diffusion coefficient) is positively correlated to Ktrans (volume transfer constant), vp( blood plasma volume fraction) and ve (extravascular extracellular space volume fraction) are positively correlated to D* and ADC (apparent diffusion coefficient), respectively. These initial results show the feasibility of characterizing diffusion and perfusion parameters using IVIM- and DCE- MRI in neck nodal metastases. In future, these techniques may be useful in assessing early treatment response in head and neck cancer patients.