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Abstract #3215

The Relationship between Knee Cartilage MR T2 & Morphology in Subjects from the Incidence & Control Cohorts of the Osteoarthritis Initiative

Gabby B. Joseph1, Thomas Baum1, Julio Carballido-Gamio1, Lorenzo Nardo1, Warapat Virayavanich1, Hamza Alizai1, Michael C. Nevitt2, John A. Lynch2, Charles E. McCulloch2, Sharmila Majumdar1, Thomas M. Link1

1Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States; 2Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA, United States

The purpose of this study is to 1) compare the prevalence of focal knee abnormalities, the mean cartilage MR T2 relaxation time, and the spatial distribution of cartilage MR T2 relaxation times between subjects from the control and incidence cohorts of the OAI, and 2) determine the relationship between MR cartilage T2 parameters and cartilage morphology. The results indicate no significant difference in the prevalence of knee abnormalities (cartilage lesions, BME, meniscus lesions) between the incidence and control groups; however, T2 parameters (mean T2, GLCM contrast, and GLCM variance) were significantly elevated in the incidence group.