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Abstract #3217

In Vivo Sodium & Proton T1rho MR Imaging of Human Knee Cartilage at 3T

Chan Hong Moon1, Jung-Hwan Kim1, Tiejun Zhao2, Xiang He1, Bum-Woo Park1, Kyongtae Ty Bae1

1Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 2MR Research Support, Siemens Healthcare, Pittsburgh, PA, United States

We achieved consistent T2, T1rho, and sodium concentration measurements in knee cartilages from normal subjects using an in-house dual-tuned knee coil and in-house sequences at 3T. We believe MR-based physiological and metabolic measures of knee cartilage may play an important role as imaging biomarkers for early detection of knee ostheoarthritis.