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Abstract #3258

T2-Weighted Imaging & Stimulated Echo Diffusion Tensor Imaging in Chronic Exertional Compartment Syndrome Calf Muscle

Eric Edward Sigmund1, Dabang Sui1, Philip A. Hodnett2, Kecheng Liu3, KellyAnne McGorty1, Michael Mechlin1, Jenny Bencardino1

1Radiology, New York University Langone Medical Center, New York, NY, United States; 2Department of Radiology, NYU Langone Center, New York, United States; 3Siemens Medical Systems, United States

Chronic exertional compartment syndrome (CECS) is a muscular disorder with fluid retention following exertion causing hypoperfusion and disability whose microscopic pathophysiology is not completely understood. T2-weighted imaging (T2w) and stimulated echo diffusion tensor imaging (DTI) were applied to suspected CECS patients before and after exertion. T2w signal intensity increases following exercise by at least 20% in some groups (defined as CECS positive). Diffusion eigenvalues increase in all groups following exertion by ~10%, and larger increases occur in CECS positive groups (20-40%). Fractional anisotropy also decreases in all groups following exertion, suggesting at least a partial role of myofiber dilation.