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Abstract #3273

Evaluation of Vessel Area using Time-Of-Flight MR Angiography, Contrast-Enhanced MR Angiography & CT Angiography in a Rabbit Peripheral Arterial Disease Model

Yi Xu1, Yingli Fu1, Nicole Azene1, Dorota Kedziorek1, Tina Ehtiati2, Aaron Flammang2, Bruce A. Wasserman1, Ye Qiao1, Merine Etesami1, Steven M. Shea2, Dara L. Kraitchman1

1Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University, Baltimore, MD, United States; 2Center for Applied Medical Imaging, Siemens Corporate Research, Inc., Baltimore, MD, United States

Measurement of small vessel diameters by MRA is challenging especially in ischemic disease. Our purpose was to compare vessel area measurement by TOF-MRA, ce-MRA and CTA after transplantation of mesenchymal stem cells in an animal peripheral arterial disease model. Both MRA techniques could provide an acceptable precision to measure small vessel diameters without ionizing radiation for the evaluation of an arteriogenesis therapy efficiacy.