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Abstract #3308

Carotid Plaque MRI Characteristics as a Marker of Severe Coronary Artery Disease.

Hideki Ota1, Minako Oikawa2, Morihiko Takeda3, Satoshi Yasuda3, Jun Takahashi3, Yoshitaka Ito3, Yoshihiro Fukumoto3, Hiroaki Shimokawa3, Shuichi Higano1,4, Shoki Takahashi1

1Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan; 2Sendai Red Cross Hospital, Sendai, Miyagi, Japan; 3Cardiovascular Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan; 4Sendai Radiation Oncology & Imaging Clinic, Sendai, Miyagi, Japan


We evaluated whether carotid MRI plaque characteristics and/or carotid wall thickness were associated with the severity of coronary artery disease in 43 patients with effort angina. Presence of complicated American Heart Association type-VI carotid plaque was significantly associated with the higher number of diseased coronary arteries after controlling for traditional risk factors of atherosclerosis as potential confounders (adjusted OR = 4.2, 95%CI, 1.1, 16.4, p=0.037). However, carotid wall thickness was not associated (adjusted OR, 0.75, 95%CI, 0.4, 1.4, p=0.35). In this population, carotid plaque characteristics may play a more important role than carotid wall thickness in predicting mutlivessel coronary disease.

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