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Abstract #3323

Combined Respiratory & Cardiac Triggered MRA of Congenital Heart Disease with a Blood Pool Contrast Agent

Shreyas S. Vasanawala1, Frandics P. Chan1, Beverley Newman1, Marcus T. Alley1

1Radiology, Stanford University, Stanford, CA, United States

Pediatric cardiovascular MRI is degraded by cardiac pulsation and respiratory motion. An SPGR sequence was modified to enable combined cardiac/respiratory triggering and fractional acceleration. 23 pediatric patients undergoing MRI with gadofosveset blood pool agent had triggered and non-triggered acquisitions. Anatomic structures were graded by two experienced readers in randomized blinded fashion and compared directly. Triggered images had higher scores for all structures (Wilcoxon rank-sum test, p<0.05). Triggered images were more likely to be preferred for most structures (one-sided binomial test, p<0.05). The approach enables imaging without suspended respiration, thus reducing depth of anesthesia and need for an artificial airway.