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Abstract #3365

Surgical Ventricular Restoration Fails to Improve Regional Left Ventricular Shape in Terms of Curvedness

Liang Zhong1, Yi Su2, Srikanth Sola3, Jose L. Navia3, Terrance Chua1, Ghassan Kassab4, Ru San Tan1

1National Heart Centre , Singapore, Singapore; 2Institute of High Performance Computing, A*STAR, Singapore; 3Cleveland Clinic, USA; 4Indiana University-Purdue University, Indiananpolis, USA


Adverse left ventricular (LV) remodeling begins with infarct expansion post-myocardial infarction (MI) and is followed by progressive cardiac fibrosis and impaired contractility of the remaining cardiomyocytes. Surgical ventricular restoration (SVR) has been used to treat ventricular aneurysms and that results in good patients outcomes. However, recent STICH trial reported that adding SVR to coronary bypass CABG was not associated with a greater improvement in reduced intermediate mortality. It is believed that LV dilation and distortion occurs post-SVR operation, which may contribute to worsening heart failure. This study was hence to examine the regional LV shape pre- and post SVR.