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Abstract #3370

Analysis of Segmental Myocardial Performance in Patients after Heart Transplantation

Daniela Foell1, Tobias Wengenmayer1, Bernd Andre Jung2, Elfriede Schilli1, Anna Lena Stroh1, Christoph Bode1, Jrgen Hennig2, Michael Markl2

1Cardiology & Angiology, University Hospital Freiburg, Freiburg, Germany; 2Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Germany

Regional left ventricular motion is altered in transplant rejection. We used MR tissue phase mapping to analyze segmental three-directional myocardial velocities in stable patients after heart transplantation (HTX, n=9) without signs of rejection. Compared to healthy controls (n=20) reduced segmental long-axis velocities in systole and diastole and increased diastolic radial velocities were found. These altered peak velocities might be an expression of remodeling and fibrosis in the transplanted heart. The knowledge of the alterations in regional motion in the transplanted heart under stable conditions is essential in order to use myocardial velocities as diagnostic tools in transplant rejection.