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Abstract #3377

Effects of Autologous Bone Marrow Mononuclear Cells Transplantation through Coronary Artery Bypass Grafting in Patients with Chronic Myocardial Infarction Assessed by Magnetic Resonance Imaging: A Randomized, Double Blind, Placebo-Controlled Pilot Trial

Minjie Lu1, Shihua Zhao1, Shiliang Jiang1, Sheng Liu2, Yan Zhang1, Zuoxiang He3

1Radiology, Fuwai Hospital, Beijing, China, People's Republic of; 2Cardiac Surgery, Fuwai Hospital, Beijing, China, People's Republic of; 3Nuclear Medicne, Fuwai Hospital, Beijing, China, People's Republic of


Recent studies have shown that autologous bone marrow mononuclear cell (aBM-MNC) transplantation can be effectively performed in human beings either by the coronary route or by endoventricular injections. However, scanty data are available for patients undergoing coronary artery bypass grafting (CABG).Accordingly, the aim of this study was to use an one-stop non-invasive imaging examination-MRI to evaluate the feasibility and safety of aBM-MNC transplantation in patients with chronic myocardial infarction(MI) undergoing CABG.

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