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Abstract #3390

Variations in Myocardial T1 with Cardiac Cycle at 1.5T

Xiaopeng Zhou1,2, Melanie S. Kotys3, Christian Stehning4, Stefan E. Fischer3, Scott D. Flamm1, Randolph M. Setser1

1Imaging Institute, Cleveland Clinic, Cleveland, OH, United States; 2Cleveland State University, Cleveland, OH, United States; 3Philips Healthcare, OH, United States; 4Philips Research, Hamburg, Germany

Healthy volunteers (n=5) were imaged at 1.5T to determine whether myocardial T1 varies throughout the cardiac cycle. T1 mapping was performed using MOLLI at 2 left ventricular short axis levels at end-systole, mid-diastole and end-diastole. T1 variation between time points was smaller than 8%, which demonstrates that cyclic variation of T1 is negligible at 1.5T. In addition, no regional variation in T1 was seen. The myocardial T1 values are of particular importance for the diagnosis of myocardial diseases, which warrants further study of cyclic myocardial T1 changes at higher magnetic field strengths.