Gerald Zsido1, Walter R. T. Witschey2,
Kevin Koomalsingh1, Joseph H. Gorman1, Robin Hinmon1,
James J. Pilla1, Ravinder Reddy3, Maxim Zaitsev2,
Robert Gorman1
1Cardiothoracic Surgery,
University of Pennsylvania, Philadelphia, PA, United States; 2Medical
Physics, University Medical Center Freiburg, Freiburg i. Breisgau, Baden
Wrttemburg, Germany; 3Radiology, University of Pennsylvania,
Philadelphia, PA, United States
Cardiac output progressively deteriorates following myocardial infarction on account of left ventricular myocardial infarction. Recently, a method for spin locked MRI was shown to overcome low frequency mechanisms of nuclear relaxation, enhancing relaxation and improving contrast compared to conventional T2-weighted imaging of MI. In this study, T1ρ MRI was performed in a swine model of MI to measure mean relaxation times in the myocardium, borderzone, several animals and compared to delayed contrast enhanced (DCE) MRI in a septum based model of MI,.
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