Gerald Zsido1, Walter R. T. Witschey2,
Kevin Koomalsingh1, Joseph H. Gorman1, Robin Hinmon1,
James J. Pilla1, Ravinder Reddy3, Maxim Zaitsev2,
University of Pennsylvania, Philadelphia, PA, United States; 2Medical
Physics, University Medical Center Freiburg, Freiburg i. Breisgau, Baden
Wrttemburg, Germany; 3Radiology, University of Pennsylvania,
Philadelphia, PA, United States
Cardiac output progressively deteriorates following myocardial infarction on account of left ventricular myocardial infarction. Recently, a method for spin locked MRI was shown to overcome low frequency mechanisms of nuclear relaxation, enhancing relaxation and improving contrast compared to conventional T2-weighted imaging of MI. In this study, T1ρ MRI was performed in a swine model of MI to measure mean relaxation times in the myocardium, borderzone, several animals and compared to delayed contrast enhanced (DCE) MRI in a septum based model of MI,.