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Abstract #3413

In-Vivo Validation of 5-Point PC-VIPR for Hemodynamic Assessment of the Hepatic & Splanchnic Hemodynamics in Swine

Alex Frydrychowicz1, Emily Winslow2, Dan Consigny1, Eric Niespodzany1, Eric Bultman1, Alejandro Roldn-Alzate1, Kevin M. Johnson3, Oliver Wieben4, Scott B. Reeder1

1Department of Radiology, University of Wisconsin - Madison, Madison, WI, United States; 2Department of Surgery, University of Wisconsin - Madison, Madison, WI, United States; 3Department of Medical Physics, University of Wisconsin - Madison, Madison, WI, United States; 4Departments of Radiology & Medical Physics, University of Wisconsin - Madison, Madison, WI, United States


Hepatic and splanchnic blood flow is of particular interest in liver disease such as cirrhosis and portal hypertension. However, comprehensive assessment of flow and morphology is challenging, especially because of the livers dual blood supply and complex anatomy. 4D MR velocity mapping is a promising approach to overcome shortcomings of existing diagnostic approaches. This validation study compared a novel radially undersampled 5-point velocity encoding strategy that provides high-resolution, large volume coverage and increased velocity sensitivity with the de facto standard of reference perivascular ultrasound. Excellent correlation and an acceptable measurement bias was found for both methods.