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Abstract #3426

In Vivo MR Spectroscopy of Irregularly Shaped Single Voxel using 2D-Selective RF Excitations Based on a PROPELLER Trajectory

Martin G. Busch1,2, Jrgen Finsterbusch1,2

1Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Neuroimage Nord, University Medical Centers Hamburg-Kiel-Lbeck, Hamburg-Kiel-Lbeck, Germany

Conventional single-voxel localization based on cross-sectional RF excitations suffers from partial volume effects if the target volume is not cuboidal. 2D-selective RF (2DRF) excitations are able to define an arbitrary excitation profile within a plane and can be used to adapt the voxel shape to the target. This is demonstrated in vivo in the human brain for 2DRF excitations based on a PROPELLER trajectory which allow obtaining high-resolution profiles at echo times of 30 ms. Compared to a previous in vivo study, the SNR efficiency is considerable improved because the excitation k-space centre is covered with each shot.