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Abstract #3428

Sensitivity & Localization Reliability Analysis for Spectral Localization by Multichannel Coils

Li An1, Steven Warach1, Jun Shen2

1National Institute of Neurological Disorders & Stroke, National Institutes of Health, Bethesda, MD, United States; 2National Institute of Mental Health, National Institutes of Health, Bethesda, MD, United States

A spectral localization technique for in vivo magnetic resonance spectroscopy using a multichannel receiver coil has been previously reported. The proposed technique allows a few compartmental spectra to be reconstructed from multichannel data acquired with no or very few phase encoding steps. In this work, a sensitivity parameter, a spatial response function (SRF), and a localization parameter were defined to compare the sensitivity and localization reliability between the proposed technique and SLIM (spectral localization by imaging). Phantom experiments showed that the proposed technique had higher sensitivity and localization reliability compared to SLIM.