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Abstract #3520

Simultaneous Bloch-Siegert B1 Mapping & Imaging of Hyperpolarized Pyruvate, Bicarbonate, & Lactate, in a Single Tracer Bolus

Angus Zoen Lau1,2, Albert P. Chen3, Charles H. Cunningham1,2

1Medical Biophysics, University of Toronto, Toronto, ON, Canada; 2Imaging Research, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; 3GE Healthcare, Toronto, ON, Canada

Precise determination of transmit RF power (B1+) for 13C MR is challenging due to limited natural abundance of 13C in vivo. The phase-based Bloch-Siegert shift provides a B1 mapping method independent of Mz, making it possible to encode B1 in an image of hyperpolarized magnetization.