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Abstract #3586

High Resolution Functional Mapping of Primary Motor Cortex & Primary Somatosensory Cortex in Humans at 7T

Robert Trampel1, Andreas Schfer1, Robin Martin Heidemann1, Dimo Ivanov1, Gabriele Lohmann1, Stefan Geyer1, Robert Turner1

1Max Planck Institute for Human Cognitive & Brain Sciences, Leipzig, Germany

The functional properties of the sensorimotor system have been intensively studied by functional MRI over the last decades. Typical fMRI resolution at field strengths at 3 Tesla and below enables a rough somatotopic mapping, but may not unambiguously differentiate between primary motor cortex (M1) and primary somatosensory cortex (S1). Here, we performed isotropic sub-millimeter fMRI at 7 Tesla, using a paradigm comprising finger tapping, finger movement without touching the finger tips and imagined finger movement. Spatial differences in activation in S1 and M1 could be distinguished, and also signal time courses dependent on the laminar position across M1 cortex were obtained.