Abstract #3653

BOLD Responses According to Stimulation Orders & Manipulation Methods

Geon-Ho Jahng¹, Seong-In Bae², Sabina Lim²

¹Department of Radiology, Kyung Hee University Hospital-Gangdong, Kyung Hee University, Seoul, Korea, Republic of; ²Department of Meridian & Acupuncture, Graduate School of Applied Eastern Medicine, Seoul, Korea, Republic of

To investigate the BOLD response depending on three parameters, stimulation order, manipulation method and the side (left/right) of acupoint, 14 healthy subjects were recruited and received acupuncture or placebo stimulation on left or right acupoint of ST36. To investigate the effect of the stimulation order, placebo/acupuncture stimulations were performed at the right acupoint and then left acupoint. To investigate the effect of the manipulation method, the needle was inserted and stimulated during only the activation period and then the needle was removed during the baseline scans. BOLD signals were measured at 3T MRI and investigated using SPM8.