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Abstract #3679

BOLD Signal Differences in the Somatosensory & Visual Pathways

Daniil Aksenov1,2, Limin Li1,2, Michael Miller1,2, Alice Wyrwicz1,2

1NorthShore University Health System, Evanston, IL, United States; 2Pritzker School of Medicine, University of Chicago, Chicago, IL, United States

In order to examine the local differences in BOLD signal, fMRI data were obtained from awake rabbits using either whisker or visual stimulation, and the BOLD responses in cortical and subcortical structures of the pathways were compared within and between each sensory system. Early results reveal striking differences in the shape of BOLD time courses in terms of adaptation (i.e., decrease to a plateau following an initial peak) between in the visual and whisker pathways. These results suggest that visual cerebral cortical versus subcortical and whisker cortical regions are characterized by different hemodynamic properties.