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Abstract #3684

Rat Brain Possesses a Default Mode Network

Hanbing Lu1, Qihong Zou1, William Rea1, Elliot A. Stein1, Yihong Yang1

1National Institute on Drug Abuse, NIH, Baltimore, MD, United States

We have identified coherent, spontaneous activity within a specific brain network in rats that mirrors the default mode network (DMN) previously reported in human and non-human primates, suggesting that operations performed by the DMN may be a fundamental physiological process in the mammalian brain. Our data raise interesting questions about the functions of DMN across species, and open novel opportunity to investigate the physiological basis of DMN using rodent model.