Abstract #3695

Development of Iron Oxide Nanoparticles for MRI-SPECT-Optical Imaging of Sentinel Lymph Nodes

Renata Madru¹, Pontus Kjellman², Pontus Svenmarker, Karin Wingrdh¹, Sarah Fredriksson², Anders rbom¹, Stefan Andersson-Engels, Christian Ingvar³, Linda Knutsson¹, Johan Olsrud⁴, Jimmy Ltt⁴, Freddy Sthlberg¹, Sven-Erik Strand¹

¹Medical Radiation Physics, Lund University, Lund, Sweden; ²Genovis AB, Lund, Sweden; ³Surgery, Skane University Hospital, Lund, Sweden; ⁴Center for Medical Imaging & Physiology, Skane University Hospital, Lund, Sweden

In this study a superparamagnetic iron oxide (SPIO) based contrast agent with magnetic, radioactive and fluorescent properties has been developed. The final aim is to be able to image the sentinel lymph node (SLN) thereby guiding the surgeon to find SLN in breast cancer and malignant melanoma patients.