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Abstract #3695

Development of Iron Oxide Nanoparticles for MRI-SPECT-Optical Imaging of Sentinel Lymph Nodes

Renata Madru1, Pontus Kjellman2, Pontus Svenmarker, Karin Wingrdh1, Sarah Fredriksson2, Anders rbom1, Stefan Andersson-Engels, Christian Ingvar3, Linda Knutsson1, Johan Olsrud4, Jimmy Ltt4, Freddy Sthlberg1, Sven-Erik Strand1

1Medical Radiation Physics, Lund University, Lund, Sweden; 2Genovis AB, Lund, Sweden; 3Surgery, Skane University Hospital, Lund, Sweden; 4Center for Medical Imaging & Physiology, Skane University Hospital, Lund, Sweden

In this study a superparamagnetic iron oxide (SPIO) based contrast agent with magnetic, radioactive and fluorescent properties has been developed. The final aim is to be able to image the sentinel lymph node (SLN) thereby guiding the surgeon to find SLN in breast cancer and malignant melanoma patients.