Joshua P. Yung1,2, Florian Maier3, David Fuentes1, Axel J. Krafft3, Andrew Elliott1, Michael Bock3, John D. Hazle1,2, Wolfhard Semmler3, R. Jason Stafford1,2
1Department of Imaging Physics, University of Texas M.D. Anderson Cancer Center, Houston, TX, United States; 2The University of Texas Graduate School of Biomedical Sciences, Houston, TX, United States; 3Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
In MR-guided thermal therapies, MR temperature imaging is obtained by using the PRF shift method, which relates temperature changes to the phase difference. Thus, interscan motion and temperature artifacts become an issue with this method. In this work, periodic motion is applied to an ex vivo phantom during heating. After applying a velocity navigator triggering pulse sequence, which synchronizes the temperature acquisition with the periodic motion, a Pennes bioheat model-based Kalman filter corrected errors and improved the temperature monitoring, which may allow for a more safe and efficient treatment in targets with inherent breathing motion.