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Abstract #3906

Quantitative Assessment of Perfusion & Permeability in Osteochrondritis Dissecans Lesions: Feasibility & Initial Results

Andreas P. Arnoldi1, Michael Ingrisch2, Sandra Utzschneider3, Maximilian F. Reiser1, Sabine Weckbach1

1Department of Clinical Radiology, Ludwig-Maximilians-University Munich, Munich, Bavaria, Germany; 2Josef Lissner Laboratory, Department of Clinical Radiology, Ludwig-Maximilians-University Munich, Munich, Germany; 3Department of Orthopedics, Campus Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany

Our study on perfusion quantification in 6 patients with OCD lesions of the knee and talus using a two compartment model shows the feasibility of DCE-MRI to detect lesions in patients with OCD and to quantify perfusion and permeability. This quantitative approach showing elevated perfusion and permeability parameters provides additional information on the pathophysiology of OCD, might influence disease management and provide a non-invasive tool for therapy monitoring.