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Abstract #3989

Detection of MR Perfusion Transit Time Effects in Pulsed Arterial Spin Labeling using a Model Validity Metric

Yang Wang1, Josef Pfeuffer2, Gary D. Hutchins1, Andrew J. Saykin1

1Radiology & Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States; 2MR Applications Development, Siemens Healthcare, Erlangen, Germany

Standard acquisition and processing of MR perfusion using Q2TIPS PASL images is extended by an additional acquisition and a metric analysis. A transit time compensation between slices and perfusion model validity measures are introduced to reduce artifacts by prolonged bolus transit time effects.