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Abstract #4163

Diminished Resting-State Functional Connectivity in Lateral Occipital Cortex in Early HIV Infection

Paul Foryt1,2, Xue Wang1, Renee Ochs1, Jae-Hon Chung1,2, Ying Wu1,3, Todd Parrish1, Ann B. Ragin1,3

1Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States; 2Engineering, Northwestern University, Evanston, IL, United States; 3Radiology, NorthShore University HealthSystem, Evanston, IL, United States

Using resting state functional connectivity MRI, thirty subjects, fifteen HIV+ and fifteen controls, were scanned on a 3.0T Siemens Trio to evaluate connectivity between brain networks. ICA component analysis was used on the collected data, finding that scanned HIV+ subjects had diminished connectivity within the lateral occipital cortex network, one of the main resting state networks. This network has been associated with visuospatial attention.