Abstract #4166

Differential Brain Activation Associated with the Effects of Emotional & Non-Emotional Distracters During a Delayed-Response Working Memory Task in Patients with Schizophrenia

Gwang-Won Kim¹, Moo-Suk Lee², Heoung-Keun Kang³, Tae-Jin Park⁴, Young-Chul Chung⁵, Jong-Chul Yang⁵, Gyung-Ho Chung⁶, Gwang-Woo Jeong^1,3

¹Interdisciplinary Program of Biomedical Engineering, Chonnam National University Medical School, Gwangju, Chonnam, Korea, Republic of; ²Psychiatry, Chonnam National University Hospital, Korea, Republic of; ³Radiology, Chonnam National University Hospital, Korea, Republic of; ⁴Psychology, Chonnam National University, Korea, Republic of; ⁵Psychiatry, Chonbuk National University Hospital, Korea, Republic of; ⁶Radiology, Chonbuk National University Hospital, Korea, Republic of

Impairment of working memory (WM) is an important factor of the cognitive deficits in patients with schizophrenia. Dysfunction of the dorsolateral prefrontal cortex (DLPFC) closely related to delayed-response WM is potentially involved with cognitive impairment of the WM observed in schizophrenia patients.