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Abstract #4253

Using a Mean DSI Dataset & Targeted ROIs can Increase the Specificity & Reproducibility of Manual Tractography in DSI.

Aki Nikolaidis1, Wen-Yih Isaac Tseng2,3

1National Taiwan University, Taipei City, Taipei, Taiwan; 2Center for Optoelectronic Biomedicine, National Taiwan University; 3Institute of Biomedical Engineering, National Taiwan University

Diffusion MRI has been used effectively to uncover detailed neuroanatomical information relating to many clinical disorders. Unfortunately some methodological problems persist which reduce the objectivity and specificity of the DSI method. We sought to create a new ROI selection and tractography method that could be applied to clinical settings. We believe that our method not only improves the objectivity and reproducibility of a given fiber tract, but it is also faster than manual fiber tract selection methods.