Abstract #4305

Diffusion Tensor Imaging Changes in the Spinal Cord of Amyotrophic Lateral Sclerosis Patients

Wim Van Hecke¹, Louise Emsell², Caroline Sage³, Stefan Sunaert³, Paul M. Parizel⁴

¹University of Antwerp, Antwerp, Belgium; ²The Murdoch Childrens Research Institute, Australia; ³University of Leuven, Belgium; ⁴University of Antwerp, Belgium

Diffusion tensor tractography was used to delineate the spinal cord in patients with amyotrphic lateral sclerosis (ALS) and healthy control subjects. The FA of the ALS patients was significantly lower than in the control subjects, especially in levels C3-C5.