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Abstract #4305

Diffusion Tensor Imaging Changes in the Spinal Cord of Amyotrophic Lateral Sclerosis Patients

Wim Van Hecke1, Louise Emsell2, Caroline Sage3, Stefan Sunaert3, Paul M. Parizel4

1University of Antwerp, Antwerp, Belgium; 2The Murdoch Childrens Research Institute, Australia; 3University of Leuven, Belgium; 4University of Antwerp, Belgium

Diffusion tensor tractography was used to delineate the spinal cord in patients with amyotrphic lateral sclerosis (ALS) and healthy control subjects. The FA of the ALS patients was significantly lower than in the control subjects, especially in levels C3-C5.