Abstract #4332

Application of Snapshot Inversion Recovery (SNAPIR) in Neonatal Patients with Snaphot-to-Volume-Reconstruction (SVR): A Pilot Study at 3 Tesla

Ash Ederies¹, Amy K. McGuinness², Nora Tusor¹, Joanna M. Allsop², Serena J. Counsell², Rita G. Nunes², Zhi Qing Wu², Jo V. Hajnal², Mary A. Rutherford², Christina Malamateniou²

¹Neonatal Imaging Group, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, United Kingdom; ²Robert Steiner MRI Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, United Kingdom

Previous studies on fetal patients have shown that Snapshot Inversion Recovery (SNAPIR) is a potentially robust motion-resistant T1-weighted alternative, offering improved anatomy delineation. Although multi-shot are the preferred acquisitions for imaging the neonatal brain, single-shot acquisitions such as SNAPIR may be advantageous for delineating the anatomy in the presence of neonatal motion. To compensate for the lower signal-to-noise-ratio and resolution introduced by single-shot techniques, dynamic scanning and image registration in the form of Snapshot-to-Volume-Reconstruction (SVR) may be used in combination. This pilot study discusses the benefits and challenges of SNAPIR and SVR in neonates and suggests areas for future optimisation.